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Methylfolate: What Is It, And Why Is It Important?

Methylfolate: What Is It, And Why Is It Important?

Apr 12, 2018


Nutritional supplements have become increasingly important in today’s day and age. Why? So many of the foods we eat are highly processed, meaning it’s impossible to receive all of the nutrients your body needs from food alone. 

In order to protect yourself from nutritional deficiencies and the implications they can have on your health, it’s important to be educated, listen to your body, and provide it with what it needs.

One supplement that is highly talked about today is methylfolate. This can be a tricky supplement to understand because it comes in different forms, which has lead to a lot of confusion in the health industry. 

However, your body counts on methylfolate in order to function at its best, so it’s important to know what it is, what it does for you, and how to make sure you’re getting enough! It’s an ingredient we take very seriously about including in our Nourishing Lactation Protein Powder for our mamas. 

Follow along as we break down everything you need to know about methylfolate:

What Is Methylfolate?

Methylfolate is the purest form of vitamin B9. It is essential for mood, cognition, behavior, and overall brain and body health. According to BrainMD, it helps in 4 key ways:

  1. Promotes Healthy Mood: Methylfolate is the most fully active form of folate, a vitamin that provides methyl groups that are necessary for many different brain functions, including mood. In clinical trials, it was proven to correct methyl deficiency and support positive mood and overall brain health.
  2. Highly Bioavailable Source of Methyl Groups: In order for the body to utilize dietary folates (from food or supplements), they must first be converted to methylfolate. However, more than 1 in 4 people are inefficient at converting folates to methylfolate, because the enzymes involved in the conversion process often carry mutations that impair their function (this is called MTHFR mutation). The right methylfolate supplement has the ability to bypass these enzymes and directly supply methyl to manage the body’s extensive networks of methyl metabolism.
  3. Promotes Metabolic Recycling of Homocysteine: Homocysteine is a byproduct of the same production of methylfolate and the amino acid methionine. If it builds up in the blood or other tissues, it can become toxic. However, methylfolate rids its toxic potential by facilitating the recycling of homocysteine to methionine.
  4. Supports Brain Health Across The Lifespan: Methyl, which comes from methylfolate, is needed from the moment of fertilization of the human egg through the development of the brain, heart and other organs, to birth and across the rest of the human lifespan. Our cells require methyl groups to create DNA, repair DNA damage, and regulate the utilization of DNA. Our nerve cells also rely on methyl to regulate mood and sleep. Methylfolate is necessary for both brain health and our wellbeing overall.


Your body cannot produce folate on its own, which means it’s something we have to get from the food we eat. As stated previously, though, we often don’t get enough of the nutrients we need today because of the way our food is processed, which means we then have to turn to supplements.

Methylfolate vs. Folate vs. Conventional Folic Acid

So what’s the difference between methylfolate, folate, and folic acid?

Methylfolate is the active and natural form of folate, also known as vitamin B9. When we take folic acid (folic acid is the synthetic form of folate), we rely on Methylenetetrahydrofolate reductase (MTHFR), a gene and enzyme found throughout the body that converts folic acid to its active form, L-methylfolate. This process is critical to the body having enough folate.

For those who have a gene mutation affecting the MTHFR enzyme, their bodies are unable to convert folic acid to methylfolate. For this reason, it’s important for them to take methylfolate rather than just folic acid in order for their bodies to utilize the vitamin.

If someone with a gene mutation or digestive condition takes folic acid, this can result in unmetabolized folic acid which has been linked to poor immune function and a variety of other health conditions.

Folate is the natural form of vitamin B9, it occurs naturally in some vegetables

Why Is Methylfolate Better?

Due to the risks that can be associated with taking folic acid, it has been shown that taking methylfolate is a much safer and more effective route. By taking methylfolate, you don’t have to worry if your body is actually reaping the benefits!

So why do many supplements on the market contain folic acid rather than methylfolate? Well, methylfolate is a high-end, more expensive ingredient. Whether you are someone who suffers from a condition like MTHFR or not, it’s always best methylated B Vitamins are a better option. Your body will thank you!



Am I Folic Acid Deficient?

At this point, you may be thinking, ‘Am I folate deficient?’

Folate deficiency is quite a prevalent issue, as there are over 200,000 cases in the US per year, and 30-40% of women are unable to metabolize the synthetic folate (folic acid) found in many products. When someone suffers from this condition, it can result in an insufficient number of healthy red blood cells, also known as Anemia.

So how can you tell if you’re folate deficient? Here are some symptoms to look out for:

  • Lack of energy
  • Pale skin
  • Canker sores and/or a swollen tongue
  • Irritability
  • Poor immune function
  • Premature hair graying
  • Constipation and/or bloating
  • Headaches
  • Weight loss
  • Shortness of breath

Pregnancy & Breastfeeding

Many women are aware of the importance of getting enough folic acid before and during pregnancy, however, it’s also just as important while breastfeeding.

According to WebMD, the recommended daily intake of folic acid before (it’s best to start taking folate one month before becoming pregnant) and during pregnancy is 400 micrograms (mcg). Why? 

Finding ways to incorporate folate into your diet and through supplements can help prevent birth defects of your baby’s brain, spinal cord, and neural tube. Additionally, it can help reduce your baby’s risk of other birth defects such as cleft lip, cleft palate, and certain kinds of heart defects.

In addition to protecting your baby throughout pregnancy, folate is also critical for your health. Meeting your recommended daily intake can reduce likelihood of developing Anemia, aid in DNA synthesis, and help with the rapid growth of the placenta and your developing baby.

So what about after baby is born? Breastfeeding moms need more energy and vitamins to meet their increased nutritional needs, folate being one of them. Folate is excreted in breast milk at the cost of the mother, which means if mom isn’t getting enough, baby will take from her own stores and put her at risk of folate deficiency. 

For this reason, it’s important to continue getting your recommended daily intake of folic acid during the breastfeeding period so you can provide for your little one.

Want to learn more about breastfeeding? Check out our Breastfeeding Guide For New Moms.

Ways to Incorporate Folate Into Your Diet

Folate occurs naturally in several foods, including:

  • Lentils
  • Avocados
  • Citrus fruits (papaya, oranges, grapefruit, strawberries, raspberries)
  • Dried beans, peas, and nuts
  • Dark leafy greens (spinach, collard greens, mustard greens, romaine lettuce)
  • Corn
  • Celery
  • Carrots
  • Squash

Not only are these foods rich folate, but many of them also contain other nutrients needed during pregnancy and breastfeeding, such as fiber, iron, and calcium. Consider these foods to be staples on your grocery list during this period of time, and even beyond!

When it comes to incorporating these foods into your diet, don’t be afraid to get creative! The key is to find a few recipes that you genuinely enjoy. Maybe it’s avocado toast sprinkled with chia seeds, a carrot cake flavored smoothie, or a black bean, corn, and spinach salad.

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How Majka Can Help

Here at Majka, we’re committed to creating products that fuel motherhood and fill in the nutritional gaps that might be in your diet. That’s why we’re proud to say Majka products use methylfolate, the active form of folate that is easily absorbed and metabolized by the body.

Our Nourishing Lactation Protein Powder offers 100% of the recommended DV, of methylfolate. Adding a scoop to your daily smoothie can make for the perfect snack or healthy breakfast.

Looking for smoothie recipe ideas? Be sure to check out our Ultimate Lactation Smoothie Recipe and Carrot Cake-Inspired Smoothie Recipe.


If you're looking for more information on breastfeeding and nutrition, check out these free resources and blog posts:

Milk Supply 101: How to Increase Your Milk Supply

Protein Shakes for Breastfeeding Moms

10 Herbs That Increase Milk Supply

Feeling Depleted? Replenish With This Breastfeeding Diet Guide

Essential Vitamins You Need Postpartum



 holistic nutritionist cara halberCara Halber is passionate about nourishing new moms as a Registered Holistic Nutritionist. She focuses on keeping foods delicious, simple and fast so that you can do more of what you love with more energy, clarity & peace of mind.

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